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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26947daf7eb635f58d416d043ff0aa4baa3986cf70037de18289d50a20e28ba5' 
  AND token = 'H2SwdRUr2hMiALY+D5iyFDV0g7vlmTRAywmxzCu3hUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}