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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d8261579a276bff307a692bfcec0a78f4e5c23b439366bc040321e3b417f7db' 
  AND token = '/sPo4e6NFrMprjxsTrxkCujyUSdQFy5VdgOsqsm3Fqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}