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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8c8311efb0d4cee1789a5ccc2dc45cd27ab9aa27c4570c021a3f333ef441736' 
  AND token = 'TjDmRF4CBOEikeOTCRUYPh1o/IRyTcRa9skwKCvPrg8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}