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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1b03fe37d94db396a55877c12c590f28e404f0da8730c3b06c93442c8b278d4' 
  AND token = 'gG7nYDS2GzCyOJM7F5LrH3T3qLZm227n7zQ4rcdIk0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}