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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4154477f28fd348c44076f0b8ae6616353f5d15c797268d08368cb3231e7214' 
  AND token = 'rMxZJ6GUMX4i60f4BQb4BYxHO4dD9XUih0zZ4KKVICI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}