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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81b38bf0105ac4d49a4259b99b975fcd806a864207ae6390c561f214510a4730' 
  AND token = 'k3ADcGXPOVjN7dX22gb+PozbSiWhq3rueUwnlTkkPfI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}