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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18db80634736771acb68a9ad6aa8d8d65f2b955d764c3b33f8bf6147d54fc757' 
  AND token = 'WwAPq2p7zETNVPoN90UiCKEZhOZ+reUR87abVAuXn1w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}