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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2d17148f33dd357cc21292a87d5e5b24853c2b50a7741a59156912b65da047b' 
  AND token = 'INW6lxfsy5kVcbH3W/qkez8c/SSD8R/DkuXDjKTP8mM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}