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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e3db0390d1d1b7926563a974e95d32ab061e2b70f48081dead97ae09f01dc68' 
  AND token = 'a2xEHSVpPwf+zIiTEcbWdI4nZqi9EFlo2+ZAcExx6Hs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}