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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28f81d8e3ae39df40c0280d2eb7129ee066d6c0b2bd06b7478b114d4fe3ed587' 
  AND token = 'MeiO3T3yPHLfL5ZYmPuJa3yf3ggdsAz0eTPnXAbqsxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}