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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'def8dd1ef7a09a8032f5d99c97287a750ab3b13aba396a46d964370c2d37a8c1' 
  AND token = 'HsEQfNy13sKg4uu7tAICa+0wzFa8cYuE5dXzoQ7x6vU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}