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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '167581c1a453a4b1621ab4ca19db8c622aa135363207061ffcb2ac457a034b6a' 
  AND token = 'xQgbN1L8SyIZlF3W1q+uLcxEEYyQv64Iq5khkYaw5gg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}