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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e759742e0b474703753d127c79fd2d2ec9404674166d2377fbb69d81ed7a4ce9' 
  AND token = 'enIkhEy3WjuQlvI51tiY+DIlLxz5D7ff/ixfweNKFfI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}