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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f53c1efcc2c4563cb05c39010d9e01a0927b9ce91ef73dd8d31109f6c3f6676' 
  AND token = '1qRzBLObOmycyQlk+52OIsT86f/eFbd1+DPwywwTzVw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}