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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '02593742b25062f57e2f4cd5d5a5d11d3406350eeee2e4e8557e66829e5eac53' 
  AND token = '3ZQeOcN3hcMR3ZofKDoaqIJmO8KfctQi4AOmFIOlH2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}