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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfa3a1a34ed41871f0204cbc8cf85a695bd2bb3ea7ef3846311b06389f8b7428' 
  AND token = 'vizoeARw0Qq6Fufn65eyMm0oZl6FQ4OrPzL/6g9rkgo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}