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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a8c1e2878c871c06db73462f1f0ccb96a021cdfd0bb675ec5cd3240cb74f675' 
  AND token = 'NidUR/1dyZ6wXpgoQA2YJwIU4bQt+l14ckEOJcFDHvk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}