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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '903a3be5b503e19147ac72ce2e117c5ec9bb2cfb02267220ea1d25a1ec455237' 
  AND token = 'E54oBerKhJohuMISYRXIS09euBMOIBBTBotkw0M2JPs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}