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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c4989aca2ded36a6830046aedf85285dca652074502efbf6fa4cb93d92d16a6' 
  AND token = '6qb0JMFl6i+gsuSMEBEAkJiT+NI6K6vkXB2+yA03G6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}