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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17dc5578c7f2a4f7882e6ebc8d2ff46040e4b309e3089f063f3b4697eb65a881' 
  AND token = 'FWh4sTtEACrG7PbDCOnPKXAKiwlx9klL4tKbaohjY0c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}