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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af3ea13cce652c0da5aae64b011b30ee39561ec541ffc2fe9fe7ba0cf5495432' 
  AND token = 'c974HxYVVxUdRp+kGPkQLiXpZR6I0mq5S9ZKbP9BM6E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}