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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a80ec22da26820f62a5d55ec6c88c901d6452cdd77b7f873961589b9ef5d3125' 
  AND token = 'Y/K+Nd1yz0oFBdahzSzEe6712D84cXlCbIz2Z9tg5Qc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}