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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5049a8fe79e75d0914bfd1fa15d86c15d8168569d88c3d2a0a2cea6f49a2b1e2' 
  AND token = 'Gk9NS3RCqmMaY4U4Eq6984QLAzmUOnJRnBrsvipUH7M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}