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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '726b0d9a4d44625fe1117f5b6ad9e2da4d8e2f4054a289feef7f25a81659bf9a' 
  AND token = '4JGfEHkuJZyf7uIJcVJu79i8xQ+1bnATnE2Ume/CtPc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}