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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9321d413a6f9bf55d6791f161ef24834a688898ff3c8f6c6b7dd38ceb17fa276' 
  AND token = 'hMrxSs0pCxr+YnVuTWssO9KunWsQc9Ju0KJkcQ4Rc6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}