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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1a56c94396ae4c7bdcb5df9d267d86d2fabb032b84cec8ab13b3fafcd687285' 
  AND token = 'xQRgedoOd1DvqX3pfeGdCwi7rh5/NGn14ZSWOdJzYGE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}