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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed4213c9825ac6879d8f8e7a3c5b0a7e2bc28495614809d14c54e4610682ba4c' 
  AND token = 'Tp/lLZZP5zeSxco65DVjkI0EUHsd1+M0DwMJh6f8inc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}