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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23c50c23873a03ea6b9ffa7560e58fd2ca1a07edd7a6be647ca9512a33b78f2a' 
  AND token = 'CHg/trsMZ22rM0uvytnVCNK9VoKy7wwj8zqS1QdKnDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}