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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e34e234cd15bccc5a0b6b476b94fad33390ffbd80ce8ad0f13874546f7dfb6a' 
  AND token = 'p1VFBsxYnWP0T3yrygpm4wLQ9S0Zfx7H9VYKMj88Fso=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}