SELECT 
  pfv.feature_id, 
  pfv.product_id, 
  pfv.variant_id, 
  gp.group_id 
FROM 
  cscart_product_features_values AS pfv 
  INNER JOIN cscart_product_variation_group_products AS gp ON pfv.product_id = gp.product_id 
  INNER JOIN cscart_product_variation_group_features AS gpf ON gpf.group_id = gp.group_id 
  AND gpf.feature_id = pfv.feature_id 
WHERE 
  pfv.lang_code = 'ru' 
  AND gp.group_id IN (253, 250, 245, 251, 249, 247, 246)

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "cost_info": {
      "query_cost": "22.46"
    },
    "nested_loop": [
      {
        "table": {
          "table_name": "gp",
          "access_type": "range",
          "possible_keys": [
            "PRIMARY",
            "idx_group_id"
          ],
          "key": "idx_group_id",
          "used_key_parts": [
            "group_id"
          ],
          "key_length": "3",
          "rows_examined_per_scan": 18,
          "rows_produced_per_join": 18,
          "filtered": "100.00",
          "index_condition": "(`test_uchur_k`.`gp`.`group_id` in (253,250,245,251,249,247,246))",
          "cost_info": {
            "read_cost": "8.06",
            "eval_cost": "1.80",
            "prefix_cost": "9.86",
            "data_read_per_join": "288"
          },
          "used_columns": [
            "product_id",
            "group_id"
          ]
        }
      },
      {
        "table": {
          "table_name": "gpf",
          "access_type": "ref",
          "possible_keys": [
            "PRIMARY",
            "idx_group_id"
          ],
          "key": "idx_group_id",
          "used_key_parts": [
            "group_id"
          ],
          "key_length": "3",
          "ref": [
            "test_uchur_k.gp.group_id"
          ],
          "rows_examined_per_scan": 1,
          "rows_produced_per_join": 18,
          "filtered": "100.00",
          "cost_info": {
            "read_cost": "4.50",
            "eval_cost": "1.80",
            "prefix_cost": "16.16",
            "data_read_per_join": "1K"
          },
          "used_columns": [
            "feature_id",
            "group_id"
          ]
        }
      },
      {
        "table": {
          "table_name": "pfv",
          "access_type": "ref",
          "possible_keys": [
            "PRIMARY",
            "fl",
            "lang_code",
            "product_id",
            "fpl",
            "idx_product_feature_variant_id"
          ],
          "key": "fpl",
          "used_key_parts": [
            "feature_id",
            "product_id",
            "lang_code"
          ],
          "key_length": "12",
          "ref": [
            "test_uchur_k.gpf.feature_id",
            "test_uchur_k.gp.product_id",
            "const"
          ],
          "rows_examined_per_scan": 1,
          "rows_produced_per_join": 18,
          "filtered": "100.00",
          "cost_info": {
            "read_cost": "4.50",
            "eval_cost": "1.80",
            "prefix_cost": "22.46",
            "data_read_per_join": "13K"
          },
          "used_columns": [
            "feature_id",
            "product_id",
            "variant_id",
            "lang_code"
          ]
        }
      }
    ]
  }
}

Result

feature_id product_id variant_id group_id
193 50998 1390 245
193 50999 1391 246
193 51000 1390 247
193 51001 1390 249
193 51002 1391 250
193 51003 1390 251
193 80 1390 253
193 51398 1391 253
193 51399 1392 253