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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17b21d1e0077d0a9983cc50f29c5d9a3e5b2f7a07c62e774e291b2b7fda2b5a6' 
  AND token = 'JeD5o/opXHorQgI6xyAqKedOvA0XIsen4Cs5hM9e4XM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}