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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf850958d9ab6424485f9c9f4e7c9df6faf68644aec7e29ac66a4bf1da0822cd' 
  AND token = 'mD79nCeiPsREJ7EUtdCVQtETy0zgGu9cpjCcq6dEwDA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}