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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5f6403b6759f48e96692bce9987a85ffdf781b0c9e81afc850f64578d3f8705' 
  AND token = 'obM4Ju7m3xdpiRwi+poGHQ9Q13Xq3enwUseBHA7/B2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}