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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f580216149d705b5a94e200d844e18bd8ab6436c72b2675ca7da37aeafe606f8' 
  AND token = 'D/f0T/uNSEEC5DH/eh+/epf9LIliZZBmSm/F0JJVg0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}