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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd36e7c397606d6e8c0c311bb663f99cc9703bdbb18f175f7c4d6ae3275de8ca' 
  AND token = 'KgJVCjWVR06BiaYV7K+DQubj7zn4t4RkbPJc0+HQVwk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}