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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '97ad9f3bfc3006cb823494c52c10ddeb272fc9be8a200ca5dc8c2e05f3626008' 
  AND token = 'NQBUOsTZrWSBqM+LTTBqPPAtys2vmaMXV3L/K4J8yzs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}