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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06301b5a2ffcc1467b892baacf168b14995ba9e3c7fd98b790ca6b3d23cef3a3' 
  AND token = 'Db/uUbEHkL3lvnCLjqsO/iDNQs7Fsstne5Yb4zzjeiA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}