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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4fc250fe156eb902e5ab9f8430cf74a13e754f5b9548f1966f91fb3fae3de32' 
  AND token = 'TR7xWwQtP3vcPzmMGwXrFKm+xheDqRTysed3z9J8FRs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}