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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b395e4b356539b70172b34c8a389bc1c214e3b47f5fb42aee39988cba4c09f7' 
  AND token = 'N2Gbw8TA+zbmFRKEERRfopPfwT5JtMwJChUdbTCH7o0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}