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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c281a56fbd7c6b436a6566a295f1f01fc7658a3879269da09782c6258d9c123' 
  AND token = 'I/y3sMN5PZBIP31jdI7M++JKSLbY21T1jyRChYyL2+I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}