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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3227d5d0e4c06cd16f9f793e4e5c431fd68b0024194d0de9c71f936bb4170c23' 
  AND token = 'DmT4JUH26RNJry9REgDJd+gAdfwBfO3CoBFaiJvNaTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}