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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b04888713d6b80e4225754820e7434570aa4c12ad76158b24d7784a1c756eb5' 
  AND token = '2TiS8sPxQUmTU6IRBeclNU31DN4/3aLyclOadSmKoP4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}