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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ddbeb0ec8d2818c6814b8faf524a28c49993a8f1765b718480d9c5985f90592' 
  AND token = 'cHW7LG2yDpe6hKj6Fhzcl5g3dSSY40xo4DuErzfwfGg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}