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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '286e9d87bdb025b7c42ab838eb54b0656d35b8f6f18766727fc0592a6c171901' 
  AND token = 'E28C2KZj3DljvlfOY5UooYblykHFC5XoIgBgTsWIJUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}