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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e840058b2c7905fc6bdcaef9399649c5abbe4ad0e491645f465abed8a8866780' 
  AND token = 'ZjwDQa7mOHinZtWyM/Xni6oaz3/jgWC5wChVBHtmtwE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}