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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9135195046b175ddf671ade0582e3f90e43a6e6ec591c7e573f42d12313dbe50' 
  AND token = 'ffXZrmcegx5Pz35umXJ0WTsE8W0T6l0yceDwSQ41mqw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}