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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c8e94077c9a193fc8062a46e36b090b86b65cc687a59e896b274758b4468484' 
  AND token = 'oUyCC3IXY9aVM789wlCs7SzwaHL+VPenGYvuf4VCgd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}