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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3edeec20f6d0dbe3c0dfc95bf7bdcb5c5166b4a62e4d97dcd54423f33feea79a' 
  AND token = 'ufLVx8vV0CWXIjHjxqj69No6kaE3mfIn9MkFFG5+Ke0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}