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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18e2693650917703f35d07d86bbec294e9939f37e6b0d5bd33f7f196b4d23ef8' 
  AND token = 'YVcn70Ht+4DPd+zuiYXS/8Hv//B0ELEkcDu1OazuGc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}