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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a635a3187c2844093dc19825cbfab032493f5a249a2eb3907029e27831a0504b' 
  AND token = 'pzgXiSwEwVtlf9Pn9G72QGWsrwSqWRUrSdSxP7QhzBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}